Onato-V is a fixed-dose combination medication containing Amlodipine (10 mg), a calcium channel blocker, and Valsartan (160 mg), an angiotensin II receptor blocker (ARB). This dual-action therapy is designed for the management of hypertension in patients whose blood pressure is not adequately controlled on either component alone. Amlodipine works by relaxing blood vessels through calcium channel blockade, while Valsartan blocks the action of angiotensin II, a hormone that causes vasoconstriction. This combination provides enhanced, 24-hour blood pressure lowering with convenient once-daily dosing. Clinical studies have demonstrated that combining valsartan with amlodipine significantly improves blood pressure management and enhances therapeutic outcomes in patients with hypertension

• Dual Mechanism of Action: Combines two complementary antihypertensive agents—vasodilation (Amlodipine) and angiotensin II blockade (Valsartan)—for enhanced blood pressure control.
  
• Effective Blood Pressure Control: Suitable for patients not adequately controlled on monotherapy; clinical evidence shows the combination improves blood pressure management and therapeutic outcomes
  
• Cardiovascular Protection: May reduce the risk of cardiovascular events in hypertensive patients

Composition
Each film coated tablet contains:

• Amlodipine Besylate Ph. Eur. equivalent to Amlodipine: 10 mg
• Valsartan USP: 160 mg

Direction for Use

• As directed by the physician.

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